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The Promises Treatment Centers, estimates that between five and 10 % of the patients at his treatment centers are treated with naltrexone. Those most likely to receive it are those with a history of early relapse—anyone who has been treated before and still have not had the opportunity to maintain sobriety for far more than four weeks. Using two separate drugs to lose weight can be very effective there are combinations while watching FDA now awaiting approval. When dealing with weight reduction and the those who go through it one should err on the side of caution and let the FDA do its job and demand some investigation be done so that the public recognizes the side effects and hazards of the medications before we drive them. Keep in mind that drug companies will be in business to generate money and that they would say almost anything to keep people on his or her medications. Researchers discovered that participants using this drug for the year, lost weight within a month and have kept the body weight off through the entire 56 weeks from the study. Contrave is a combination in the drugs naltrexone and bupropion, which generally seems to reflect a whole new trend of weight-loss drugs which might be made up of many active ingredient, which can make them more efficient and safer. Combo-pilling is the newest fad or also the newest ahead under scrutiny and so it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that by using a combination of pills is becoming popular could be the fact that since right now there aren't long term prescription diet pills that have been authorized by the FDA besides orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations have been rejected or have yet to be authorized by the FDA. Seizures can be a side effect with Contrave and mustn't be taken in people with seizure disorders. The drug may also raise hypertension and heartrate, and mustn't be used in people with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise hypertension and heartbeat and must not be used in patients with uncontrolled high blood pressure level, in addition to by you aren't heart-related and cerebrovascular (blood vessel dysfunction impacting the brain) disease. Patients using a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients on the increased chance of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stopping smoking. A pyromaniac, with both psychiatric and medical therapy, can still be treated. It is best done with behavioral therapy. Psychotherapy treatment alongside behavior modification is among the most frequently used treatment. Based on the study of Jon Grant, a compounding treatment of drugs and behavioral therapy was discovered to be successful for treating pyromania. The using serotonin reuptake inhibitors is also beneficial in managing the impulsive behavior from the patient like other impulse control disorder. Also ideal for the patient are medications for example Lithium, naltrexone, (ReVia), fluoxetine (Prozac), citalopram (Celexa), paroxetene (Paxil), and other antidepressants.